Regenerative potential of prostate luminal cells revealed by single-cell analysis

Androgen deprivation is the cornerstone of prostate cancer treatment. It results in involution of the normal gland to ~90% of its original size because of the loss of luminal cells. The prostate regenerates when androgen is restored, a process postulated to involve stem cells. Using single-cel RNA s...

Täydet tiedot

Bibliografiset tiedot
Päätekijät: Karthaus, Wouter R, Hofree, Matan, Choi, Danielle, Linton, Eliot L, Turkekul, Mesruh, Bejnood, Alborz, Carver, Brett, Gopalan, Anuradha, Abida, Wassim, Laudone, Vincent, Biton, Moshe, Chaudhary, Ojasvi, Xu, Tianhao, Masilionis, Ignas, Manova, Katia, Mazutis, Linas, Pe’er, Dana, Regev, Aviv, Sawyers, Charles L
Muut tekijät: Koch Institute for Integrative Cancer Research at MIT
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: American Association for the Advancement of Science (AAAS) 2021
Linkit:https://hdl.handle.net/1721.1/136008