H3.3 Nucleosome Assembly Mutants Display a Late-Onset Maternal Effect

© 2020 Elsevier Inc. Burkhart et al. show that mutants lacking components of H3.3 assembly complexes have pleiotropic defects that manifest near the onset of adulthood. Mitochondrial stress likely contributes to these late-onset defects. The late-onset defects of H3.3 assembly mutants can be materna...

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Bibliographic Details
Main Authors: Burkhart, Kirk B, Sando, Steven R, Corrionero, Anna, Horvitz, H Robert
Other Authors: Howard Hughes Medical Institute
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/136022