Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance

Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance

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© 2020 Cancer relapse begins when malignant cells pass through the extreme metabolic bottleneck of stress from chemotherapy and the byproducts of the massive cell death in the surrounding region. In acute myeloid leukemia, complete remissions are common, but few are cured. We tracked leukemia cells...

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Bibliographic Details
Main Authors: van Gastel, Nick, Spinelli, Jessica B, Sharda, Azeem, Schajnovitz, Amir, Baryawno, Ninib, Rhee, Catherine, Oki, Toshihiko, Grace, Eliane, Soled, Heather J, Milosevic, Jelena, Sykes, David B, Hsu, Peggy P, Vander Heiden, Matthew G, Vidoudez, Charles, Trauger, Sunia A, Haigis, Marcia C, Scadden, David T
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/136165

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https://hdl.handle.net/1721.1/136165

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