The Taste Receptor TAS1R3 Regulates Small Intestinal Tuft Cell Homeostasis

Tuft cells are an epithelial cell type critical for initiating type 2 immune responses to parasites and protozoa in the small intestine. To respond to these stimuli, intestinal tuft cells use taste chemosensory signaling pathways, but the role of taste receptors in type 2 immunity is poorly understo...

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Bibliographic Details
Main Authors: Howitt, Michael R, Cao, Y Grace, Gologorsky, Matthew B, Li, Jessica A, Haber, Adam L, Biton, Moshe, Lang, Jessica, Michaud, Monia, Regev, Aviv, Garrett, Wendy S
Other Authors: Howard Hughes Medical Institute
Format: Article
Language:English
Published: The American Association of Immunologists 2021
Online Access:https://hdl.handle.net/1721.1/136260