Structural basis for the docking of mTORC1 on the lysosomal surface

Structural basis for the docking of mTORC1 on the lysosomal surface

© 2019 American Association for the Advancement of Science. All rights reserved. The mTORC1 (mechanistic target of rapamycin complex 1) protein kinase regulates growth in response to nutrients and growth factors. Nutrients promote its translocation to the lysosomal surface, where its Raptor subunit...

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Bibliographic Details
Main Authors: Rogala, Kacper B, Gu, Xin, Kedir, Jibril F, Abu-Remaileh, Monther, Bianchi, Laura F, Bottino, Alexia MS, Dueholm, Rikke, Niehaus, Anna, Overwijn, Daan, Fils, Ange-Célia Priso, Zhou, Sherry X, Leary, Daniel, Laqtom, Nouf N, Brignole, Edward J, Sabatini, David M
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/136463

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https://hdl.handle.net/1721.1/136463

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