An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques

© 2020 Elsevier Inc. Optogenetics is among the most widely employed techniques to manipulate neuronal activity. However, a major drawback is the need for invasive implantation of optical fibers. To develop a minimally invasive optogenetic method that overcomes this challenge, we engineered a new ste...

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Bibliographic Details
Main Authors: Gong, Xin, Mendoza-Halliday, Diego, Ting, Jonathan T, Kaiser, Tobias, Sun, Xuyun, Bastos, André M, Wimmer, Ralf D, Guo, Baolin, Chen, Qian, Zhou, Yang, Pruner, Maxwell, Wu, Carolyn W-H, Park, Demian, Deisseroth, Karl, Barak, Boaz, Boyden, Edward S, Miller, Earl K, Halassa, Michael M, Fu, Zhanyan, Bi, Guoqiang, Desimone, Robert, Feng, Guoping
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/136482