Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing
A high-throughput method for amplication-free single-cell whole-genome sequencing can be scaled up to analyze tens of thousands of cells from different tissues and clinical sample types and identifies replication states, aneuploidies, and subclonal mutations.
Main Author: | Boyden, Edward |
---|---|
Other Authors: | Massachusetts Institute of Technology. Media Laboratory |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2022
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Online Access: | https://hdl.handle.net/1721.1/136528.2 |
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