A computational model of mutual antagonism in the mechano-signaling network of RhoA and nitric oxide

Abstract Background RhoA is a master regulator of cytoskeletal contractility, while nitric oxide (NO) is a master regulator of relaxation, e.g., vasodilation. There are multiple forms of cross-talk between the RhoA/ROCK pathway and the eNOS/NO/cGMP p...

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Bibliographic Details
Main Authors: Surendran, Akila, Forbes Dewey, C., Low, Boon C., Tucker-Kellogg, Lisa
Other Authors: Singapore-MIT Alliance in Research and Technology (SMART)
Format: Article
Language:English
Published: BioMed Central 2021
Online Access:https://hdl.handle.net/1721.1/136743