A flexible ChIP-sequencing simulation toolkit

Abstract Background A major challenge in evaluating quantitative ChIP-seq analyses, such as peak calling and differential binding, is a lack of reliable ground truth data. Accurate simulation of ChIP-seq data can mitigate this challenge, but existing...

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Bibliographic Details
Main Authors: Zheng, An, Lamkin, Michael, Qiu, Yutong, Ren, Kevin, Goren, Alon, Gymrek, Melissa
Other Authors: Massachusetts Institute of Technology. Department of Mathematics
Format: Article
Language:English
Published: BioMed Central 2021
Online Access:https://hdl.handle.net/1721.1/136788