Ribonuclease zymogen induces cytotoxicity upon HIV-1 infection

Abstract Background Targeting RNA is a promising yet underdeveloped modality for the selective killing of cells infected with HIV-1. The secretory ribonucleases (RNases) found in vertebrates have cytotoxic ribonucleolytic activity that is kept in che...

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Bibliographic Details
Main Authors: Windsor, Ian W., Dudley, Dawn M., O’Connor, David H., Raines, Ronald T.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: BioMed Central 2021
Online Access:https://hdl.handle.net/1721.1/136960