The Immediate Early Gene Arc Is Not Required for Hippocampal Long-Term Potentiation

Memory consolidation is thought to occur through protein synthesis-dependent synaptic plasticity mechanisms such as long-term potentiation (LTP). Dynamic changes in gene expression and epigenetic modifications underlie the maintenance of LTP. Similar mechanisms may mediate the storage of memory. Key...

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Bibliographic Details
Main Authors: Kyrke-Smith, Madeleine, Volk, Lenora J., Cooke, Samuel F., Bear, Mark F., Huganir, Richard L., Shepherd, Jason D.
Other Authors: Picower Institute for Learning and Memory
Format: Article
Language:English
Published: Society for Neuroscience 2022
Online Access:https://hdl.handle.net/1721.1/138162.2