Comparing Native Crystal Structures and AlphaFold2 Predicted Water-Soluble G Protein-Coupled Receptor QTY Variants

Accurate predictions of 3-dimensional protein structures by AlphaFold2 is a game-changer for biology, especially for structural biology. Here we present the studies of several native chemokine receptors including CCR5, CCR9, CXCR2 and CXCR4 determined by X-ray crystallography, and their water-solubl...

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Bibliographic Details
Main Authors: Skuhersky, Michael A., Tao, Fei, Qing, Rui, Smorodina, Eva, Jin, David, Zhang, Shuguang
Other Authors: Massachusetts Institute of Technology. Media Laboratory
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2021
Online Access:https://hdl.handle.net/1721.1/138236