Selective Neuronal Vulnerability in Alzheimer’s Disease: A Network-Based Analysis

© 2020 The Authors Neurons display different levels of vulnerability to Alzheimer's pathology. Roussarie et al. experimentally profile and computationally model several relevant neuron types. Using a mouse-human framework, they identify genes linking Aß, aging, and tau in vulnerable neurons. Fi...

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Bibliographic Details
Main Authors: Roussarie, Jean-Pierre, Yao, Vicky, Rodriguez-Rodriguez, Patricia, Oughtred, Rose, Rust, Jennifer, Plautz, Zakary, Kasturia, Shirin, Albornoz, Christian, Wang, Wei, Schmidt, Eric F, Dannenfelser, Ruth, Tadych, Alicja, Brichta, Lars, Barnea-Cramer, Alona, Heintz, Nathaniel, Hof, Patrick R, Heiman, Myriam, Dolinski, Kara, Flajolet, Marc, Troyanskaya, Olga G, Greengard, Paul
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/138269