A Survey of Genome Editing Activity for 16 Cas12a Orthologs

© 2019 by The Keio Journal of Medicine. The class 2 CRISPR-Cas endonuclease Cas12a (previously known as Cpf1) offers several advantages over Cas9, including the ability to process its own array and the requirement for just a single RNA guide. These attributes make Cas12a promising for many genome en...

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Bibliographic Details
Main Authors: Zetsche, Bernd, Abudayyeh, Omar O, Gootenberg, Jonathan S, Scott, David A, Zhang, Feng
Format: Article
Language:English
Published: Keio Journal of Medicine 2021
Online Access:https://hdl.handle.net/1721.1/138386