Molecular basis of CTCF binding polarity in genome folding

Molecular basis of CTCF binding polarity in genome folding

© 2020, The Author(s). Current models propose that boundaries of mammalian topologically associating domains (TADs) arise from the ability of the CTCF protein to stop extrusion of chromatin loops by cohesin. While the orientation of CTCF motifs determines which pairs of CTCF sites preferentially sta...

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Bibliographic Details
Main Authors: Nora, Elphège P, Caccianini, Laura, Fudenberg, Geoffrey, So, Kevin, Kameswaran, Vasumathi, Nagle, Abigail, Uebersohn, Alec, Hajj, Bassam, Saux, Agnès Le, Coulon, Antoine, Mirny, Leonid A, Pollard, Katherine S, Dahan, Maxime, Bruneau, Benoit G
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/138402

Internet

https://hdl.handle.net/1721.1/138402

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