T Follicular Regulatory Cell–Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity

© 2020 by The American Association of Immunologists, Inc. T follicular regulatory (TFR) cells limit Ab responses, but the underlying mechanisms remain largely unknown. In this study, we identify Fgl2 as a soluble TFR cell effector molecule through single-cell gene expression profiling. Highly expres...

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Bibliographic Details
Main Authors: Sungnak, Waradon, Wagner, Allon, Kowalczyk, Monika S, Bod, Lloyd, Kye, Yoon-Chul, Sage, Peter T, Sharpe, Arlene H, Sobel, Raymond A, Quintana, Francisco J, Rozenblatt-Rosen, Orit, Regev, Aviv, Wang, Chao, Yosef, Nir, Kuchroo, Vijay K
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: The American Association of Immunologists 2021
Online Access:https://hdl.handle.net/1721.1/138496