Using machine learning to increase the predictive value of humanized mouse models for the human immune response to YFV-17D

Despite their utility as models for human systems, intrinsic differences between mouse and human biology limit direct translation of findings. Immunocompromised mice have been engrafted with functional human immune system components, or “humanized”, to better model the human immune response. Continu...

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Detalhes bibliográficos
Autor principal: Ravinder, Divya
Outros Autores: Lauffenburger, Douglas A.
Formato: Tese
Publicado em: Massachusetts Institute of Technology 2022
Acesso em linha:https://hdl.handle.net/1721.1/139044