Using machine learning to increase the predictive value of humanized mouse models for the human immune response to YFV-17D
Despite their utility as models for human systems, intrinsic differences between mouse and human biology limit direct translation of findings. Immunocompromised mice have been engrafted with functional human immune system components, or “humanized”, to better model the human immune response. Continu...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/139044 |