Design of Post-Translationally Modified Peptides by Combining Enzymes from Diverse Pathways
Over the past decade, ribosomally-synthesized and post-translationally modified peptides (RiPPs) have emerged as both therapeutically-relevant and engineerable, two traits previously unobserved together in a natural product class. Their biosynthesis is modular: a precursor peptide recruits enzymes t...
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/139218 http://orcid.org/0000-0002-7603-8203 |