Evolution of large palindromes on the primate X chromosome
Human sex chromosomes are enriched for complex genomic architecture, including massive palindromes with arms that can exceed 1 Mb in length and arm-to-arm sequence identity higher than 99%. Palindrome arms harbor protein-coding genes with testis-biased expression, suggesting roles in male fertility....
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Format: | Thesis |
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Massachusetts Institute of Technology
2022
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Online Access: | https://hdl.handle.net/1721.1/139389 |