Characterization of anti-tumor T cell specificities to inform engineering of antigen-targeted immunotherapies
Over the past several decades, advances in immunotherapy have revolutionized cancer treatment. Immune checkpoint blockade has resulted in durable responses for some patients, but others have not seen the same benefits. T cells are essential to the success of many immunotherapies, as their receptors...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/140200 https://orcid.org/0000-0003-1147-3228 |