1H detection and dynamic nuclear polarization–enhanced NMR of Aβ1-42 fibrils

Several publications describing high-resolution structures of amyloid-β (Aβ) and other fibrils have demonstrated that magic-angle spinning (MAS) NMR spectroscopy is an ideal tool for studying amyloids at atomic resolution. Nonetheless, MAS NMR suffers from low sensitivity, requiring relatively large...

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Bibliographic Details
Main Authors: Bahri, Salima, Silvers, Robert, Michael, Brian, Jaudzems, Kristaps, Lalli, Daniela, Casano, Gilles, Ouari, Olivier, Lesage, Anne, Pintacuda, Guido, Linse, Sara, Griffin, Robert G
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2022
Online Access:https://hdl.handle.net/1721.1/141068