A Concise Route to MK-4482 (EIDD-2801) from Cytidine: Part 2

© 2021 Georg Thieme Verlag. All rights reserved. A new route to MK-4482 was developed. The route replaces uridine with the more available and less expensive cytidine. Low-cost, simple reagents are used for the chemical transformations, and the yield is improved from 17% to 44%. A step is removed fro...

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Bibliographic Details
Main Authors: Gopalsamuthiram, Vijayagopal, Williams, Corshai, Noble, Jeffrey, Jamison, Tim, Gupton, B Frank, Snead, David R
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2022
Online Access:https://hdl.handle.net/1721.1/141086