Enterobactin- and salmochelin-β-lactam conjugates induce cell morphologies consistent with inhibition of penicillin-binding proteins in uropathogenic Escherichia coli CFT073

The design and synthesis of narrow-spectrum antibiotics that target a specific bacterial strain, species, or group of species is a promising strategy for treating bacterial infections when the causative agent is known. In this work, we report the synthesis and evaluation of four new siderophore-β-la...

Full description

Bibliographic Details
Main Authors: Sargun, Artur, Johnstone, Timothy C, Zhi, Hui, Raffatellu, Manuela, Nolan, Elizabeth M
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Royal Society of Chemistry (RSC) 2022
Online Access:https://hdl.handle.net/1721.1/141193