Phosphorylation-Dependent Conformations of the Disordered Carboxyl-Terminus Domain in the Epidermal Growth Factor Receptor

Phosphorylation-Dependent Conformations of the Disordered Carboxyl-Terminus Domain in the Epidermal Growth Factor Receptor

© 2020 American Chemical Society. All rights reserved. The epidermal growth factor receptor (EGFR), a receptor tyrosine kinase, regulates basic cellular functions and is a major target for anticancer therapeutics. The carboxyl-terminus domain is a disordered region of EGFR that contains the tyrosine...

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Bibliographic Details
Main Authors: Regmi, Raju, Srinivasan, Shwetha, Latham, Andrew P, Kukshal, Vandna, Cui, Weidong, Zhang, Bin, Bose, Ron, Schlau-Cohen, Gabriela S
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: American Chemical Society (ACS) 2022
Online Access:https://hdl.handle.net/1721.1/141242

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https://hdl.handle.net/1721.1/141242

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