Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells

Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells

© 2020 Pae et al. During affinity maturation, germinal center (GC) B cells alternate between proliferation and somatic hypermutation in the dark zone (DZ) and affinity-dependent selection in the light zone (LZ). This anatomical segregation imposes that the vigorous proliferation that allows clonal e...

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Bibliographic Details
Main Authors: Pae, Juhee, Ersching, Jonatan, Castro, Tiago BR, Schips, Marta, Mesin, Luka, Allon, Samuel J, Ordovas-Montanes, Jose, Mlynarczyk, Coraline, Melnick, Ari, Efeyan, Alejo, Shalek, Alex K, Meyer-Hermann, Michael, Victora, Gabriel D
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Rockefeller University Press 2022
Online Access:https://hdl.handle.net/1721.1/141292

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https://hdl.handle.net/1721.1/141292

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