Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer
Prognostically relevant RNA expression states exist in pancreatic ductal adenocarcinoma (PDAC), but our understanding of their drivers, stability, and relationship to therapeutic response is limited. To examine these attributes systematically, we profiled metastatic biopsies and matched organoid mod...
Format: | Article |
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Language: | English |
Published: |
Elsevier BV
2022
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Online Access: | https://hdl.handle.net/1721.1/141304 |