Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2.
Effective presentation of antigens by human leukocyte antigen (HLA) class I molecules to CD8+ T cells is required for viral elimination and generation of long-term immunological memory. In this study, we applied a single-cell, multiomic technology to generate a unified ex vivo characterization of th...
| Format: | Article |
|---|---|
| Language: | English |
| Published: |
2022
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| Online Access: | https://hdl.handle.net/1721.1/141305 |