Data-Driven Polymer Model for Mechanistic Exploration of Diploid Genome Organization

© 2020 Biophysical Society Chromosomes are positioned nonrandomly inside the nucleus to coordinate with their transcriptional activity. The molecular mechanisms that dictate the global genome organization and the nuclear localization of individual chromosomes are not fully understood. We introduce a...

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Bibliographic Details
Main Authors: Qi, Yifeng, Reyes, Alejandro, Johnstone, Sarah E, Aryee, Martin J, Bernstein, Bradley E, Zhang, Bin
Format: Article
Language:English
Published: Elsevier BV 2022
Online Access:https://hdl.handle.net/1721.1/141342