Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin

© 2020 National Academy of Sciences. All rights reserved. Polycomb repressive complex 2 (PRC2) installs and spreads repressive histone methylation marks on eukaryotic chromosomes. Because of the key roles that PRC2 plays in development and disease, how this epigenetic machinery interacts with DNA an...

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Bibliographic Details
Main Authors: Leicher, Rachel, Ge, Eva J, Lin, Xingcheng, Reynolds, Matthew J, Xie, Wenjun, Walz, Thomas, Zhang, Bin, Muir, Tom W, Liu, Shixin
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: National Academy of Sciences 2022
Online Access:https://hdl.handle.net/1721.1/141343.2