Multiscale modeling of genome organization with maximum entropy optimization

Three-dimensional (3D) organization of the human genome plays an essential role in all DNA-templated processes, including gene transcription, gene regulation, and DNA replication. Computational modeling can be an effective way of building high-resolution genome structures and improving our understan...

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Bibliographic Details
Main Authors: Lin, Xingcheng, Qi, Yifeng, Latham, Andrew P, Zhang, Bin
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: AIP Publishing 2022
Online Access:https://hdl.handle.net/1721.1/141348