Multiscale modeling of genome organization with maximum entropy optimization
Three-dimensional (3D) organization of the human genome plays an essential role in all DNA-templated processes, including gene transcription, gene regulation, and DNA replication. Computational modeling can be an effective way of building high-resolution genome structures and improving our understan...
Main Authors: | Lin, Xingcheng, Qi, Yifeng, Latham, Andrew P, Zhang, Bin |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | English |
Published: |
AIP Publishing
2022
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Online Access: | https://hdl.handle.net/1721.1/141348 |
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