Inferring the intrinsic mutational fitness landscape of influenzalike evolving antigens from temporally ordered sequence data

There still are no effective long-term protective vaccines against viruses that continuously evolve under immune pressure such as seasonal influenza, which has caused, and can cause, devastating epidemics in the human population. To find such a broadly protective immunization strategy, it is useful...

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Bibliographic Details
Main Authors: Doelger, Julia, Kardar, Mehran, Chakraborty, Arup K
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: American Physical Society (APS) 2022
Online Access:https://hdl.handle.net/1721.1/141984