The widespread IS200/IS605 transposon family encodes diverse programmable RNA-guided endonucleases
IscB proteins are putative nucleases encoded in a distinct family of IS200/IS605 transposons and are likely ancestors of the RNA-guided endonuclease Cas9, but the functions of IscB and its interactions with any RNA remain uncharacterized. Using evolutionary analysis, RNA sequencing, and biochemical...
Հիմնական հեղինակներ: | , , , , , , , , , , , |
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Այլ հեղինակներ: | |
Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
American Association for the Advancement of Science (AAAS)
2022
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Առցանց հասանելիություն: | https://hdl.handle.net/1721.1/142061 |