Stiffness of targeted layer-by-layer nanoparticles impacts elimination half-life, tumor accumulation, and tumor penetration

Stiffness of targeted layer-by-layer nanoparticles impacts elimination half-life, tumor accumulation, and tumor penetration

<jats:title>Significance</jats:title> <jats:p>Layer-by-layer nanoparticles (LbL NPs), comprised of a charged core substrate layered sequentially with oppositely charged polyelectrolytes, are a promising class of drug delivery carriers for cancer therapeutics with demonst...

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Bibliographic Details
Main Authors: Kong, Stephanie M, Costa, Daniel F, Jagielska, Anna, Van Vliet, Krystyn J, Hammond, Paula T
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2022
Online Access:https://hdl.handle.net/1721.1/142567

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https://hdl.handle.net/1721.1/142567

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