Regulation of miRNA degradation

miRNAs are small RNAs that repress gene expression by guiding the effector protein Argonaute (Ago) to complementary sites in the 3′ UTRs of target genes. The levels of a miRNA in a given cell-type are determined by the balance of its rates of production and decay. Although much is known about miRNA...

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Bibliographic Details
Main Author: Kingston, Elena Ruth
Other Authors: Bartel, David
Format: Thesis
Published: Massachusetts Institute of Technology 2022
Online Access:https://hdl.handle.net/1721.1/142683