Regulation of miRNA degradation
miRNAs are small RNAs that repress gene expression by guiding the effector protein Argonaute (Ago) to complementary sites in the 3′ UTRs of target genes. The levels of a miRNA in a given cell-type are determined by the balance of its rates of production and decay. Although much is known about miRNA...
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Format: | Thesis |
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Massachusetts Institute of Technology
2022
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Online Access: | https://hdl.handle.net/1721.1/142683 |