Biomolecular Condensates in Transcriptional Regulation
Transcriptional regulation of gene expression is fundamental in determining cell behavior, identity, and organism development. When dysregulated it can cause disease. Core to transcriptional regulation is the control of RNA polymerase II (RNAPII) activity. The combined activity of DNA regulatory ele...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/142692 |