Metabolic regulation of mammalian cell growth and proliferation

Proliferation requires that cells acquire sufficient biomass to produce two daughter cells. To accomplish this, cells must utilize available nutrients to generate new components of cell mass, including proteins, lipids, and nucleic acids. In addition, cells must coordinate biosynthesis and productio...

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Bibliographic Details
Main Author: Diehl, Frances Flewelling
Other Authors: Vander Heiden, Matthew G.
Format: Thesis
Published: Massachusetts Institute of Technology 2022
Online Access:https://hdl.handle.net/1721.1/142699