Quasi-potential analysis of multi-variate stochastic differential equations
Genetic circuit motifs based on two transcription factors can model cell-fate decisions critical for embryonic development and adult homeostasis. One important such motif is the self-activating toggle switch allows for tri-stable configuration and is believed to be responsible for stem-cell differen...
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Format: | Thesis |
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Massachusetts Institute of Technology
2022
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Online Access: | https://hdl.handle.net/1721.1/142704 |