Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function

The utility of in vitro human disease models is mainly dependent on the availability and functional maturity of tissue-specific cell types. We have previously screened for and identified small molecules that can enhance hepatocyte function in vitro. Here, we characterize the functional effects of on...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Schepers, Arnout G, Shan, Jing, Cox, Andrew G, Huang, Ada, Evans, Helen, Walesky, Chad, Fleming, Heather E, Goessling, Wolfram, Bhatia, Sangeeta N
Format: Artikel
Sprache:English
Veröffentlicht: American Chemical Society (ACS) 2022
Online Zugang:https://hdl.handle.net/1721.1/142801