Sub-Picomolar Detection of SARS-CoV-2 RBD via Computationally-Optimized Peptide Beacons
The novel coronavirus SARS-CoV-2 continues to pose a significant global health threat. Along with vaccines and targeted therapeutics, there is a critical need for rapid diagnostic solutions. In this work, we employ a deep learning-based protein design to engineer molecular beacons that function as c...
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Format: | Thesis |
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Massachusetts Institute of Technology
2022
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Online Access: | https://hdl.handle.net/1721.1/142839 https://orcid.org/0000-0001-5778-4430 |