Synthetic Circuit-Driven Expression of Heterologous Enzymes for Disease Detection

Synthetic Circuit-Driven Expression of Heterologous Enzymes for Disease Detection

The integration of nanotechnology and synthetic biology could lay the framework for new classes of engineered biosensors that produce amplified readouts of disease states. As a proof-of-concept demonstration of this vision, here we present an engineered gene circuit that, in response to cancer-assoc...

Full description

Bibliographic Details
Main Authors: He, Jiang, Nissim, Lior, Soleimany, Ava P, Binder-Nissim, Adina, Fleming, Heather E, Lu, Timothy K, Bhatia, Sangeeta N
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: American Chemical Society (ACS) 2022
Online Access:https://hdl.handle.net/1721.1/142861

Internet

https://hdl.handle.net/1721.1/142861

Similar Items