Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity
The global decline in malaria has stalled1, emphasizing the need for vaccines that induce durable sterilizing immunity. Here we optimized regimens for chemoprophylaxis vaccination (CVac), for which aseptic, purified, cryopreserved, infectious Plasmodium falciparum sporozoites (PfSPZ) were inoculated...
Hovedforfatter: | |
---|---|
Andre forfattere: | |
Format: | Article |
Sprog: | English |
Udgivet: |
Springer Science and Business Media LLC
2022
|
Online adgang: | https://hdl.handle.net/1721.1/142862 |