Two chemoattenuated PfSPZ malaria vaccines induce sterile hepatic immunity

The global decline in malaria has stalled1, emphasizing the need for vaccines that induce durable sterilizing immunity. Here we optimized regimens for chemoprophylaxis vaccination (CVac), for which aseptic, purified, cryopreserved, infectious Plasmodium falciparum sporozoites (PfSPZ) were inoculated...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter: Bhatia, Sangeeta
Andre forfattere: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Sprog:English
Udgivet: Springer Science and Business Media LLC 2022
Online adgang:https://hdl.handle.net/1721.1/142862