Tissue catabolism and donor-specific dexamethasone response in a human osteochondral model of post-traumatic osteoarthritis

Abstract Background Post-traumatic osteoarthritis (PTOA) does not currently have clinical prognostic biomarkers or disease-modifying drugs, though promising candidates such as dexamethasone (Dex) exist. Many challenges in studying and treating this d...

Full description

Bibliographic Details
Main Authors: Black, Rebecca M., Flaman, Lisa L., Lindblom, Karin, Chubinskaya, Susan, Grodzinsky, Alan J., Önnerfjord, Patrik
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: BioMed Central 2022
Online Access:https://hdl.handle.net/1721.1/143088