Scaling up Genetic Circuits in Mammalian Cells: A U1-snRNA-based Platform Enables Mammalian Cells to Compute the Bitwise Inversion of the Square Root of a Number
Scaling up genetic circuits in mammalian cells can lead to a new class of therapies. As a result of my research as PhD candidate on exploring ways and engineering tools to scale up genetic circuits, I engineered and validated in HEK293FT cells a genetic circuit that allows those cells to compute the...
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/143233 |