Data-driven Mechanistic Modeling of 3D Human Genome
Three-dimensional (3D) organization of the human genome regulates DNA-templated processes, including gene transcription, gene regulation, and DNA replication, which are crucial for cell differentiation and cell functionality. Computational modeling serves as an efficient and effective way of buildin...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/143360 |