Elucidating the functional states of tumor-resident dendritic cells that drive productive anti-tumor immunity
While checkpoint blockade immunotherapy (CBT) has demonstrated remarkable clinical efficacy, its success is tempered by an inability to induce responses in the majority of cancer patients. Efforts to understand mechanisms of CBT resistance have unveiled a requirement for a subset of dendritic cells...
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| Format: | Thesis |
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Massachusetts Institute of Technology
2022
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| Online Access: | https://hdl.handle.net/1721.1/143425 |