Tau induces formation of α-synuclein filaments with distinct molecular conformations

Recent structural investigation of amyloid filaments extracted from human patients demonstrated that the ex vivo filaments associated with different disease phenotypes adopt diverse molecular conformations, which are different from those of in vitro amyloid filaments. A very recent cryo-EM structura...

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Bibliographic Details
Main Authors: Hojjatian, Alimohammad, Dasari, Anvesh KR, Sengupta, Urmi, Taylor, Dianne, Daneshparvar, Nadia, Yeganeh, Fatemeh Abbasi, Dillard, Lucas, Michael, Brian, Griffin, Robert G, Borgnia, Mario J, Kayed, Rakez, Taylor, Kenneth A, Lim, Kwang Hun
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Elsevier BV 2022
Online Access:https://hdl.handle.net/1721.1/143441