Vaccination reshapes the virus-specific T cell repertoire in unexposed adults

Vaccination reshapes the virus-specific T cell repertoire in unexposed adults

We examined how baseline CD4+ T cell repertoire and precursor states impact responses to pathogen infection in humans using primary immunization with yellow fever virus (YFV) vaccine. YFV-specific T cells in unexposed individuals were identified by peptide-MHC tetramer staining and tracked pre- and...

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Bibliographic Details
Main Authors: Pan, Yi-Gen, Aiamkitsumrit, Benjamas, Bartolo, Laurent, Wang, Yifeng, Lavery, Criswell, Marc, Adam, Holec, Patrick V, Rappazzo, C Garrett, Eilola, Theresa, Gimotty, Phyllis A, Hensley, Scott E, Antia, Rustom, Zarnitsyna, Veronika I, Birnbaum, Michael E, Su, Laura F
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Elsevier BV 2022
Online Access:https://hdl.handle.net/1721.1/143450

Internet

https://hdl.handle.net/1721.1/143450

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