Inflammation resolution circuits are uncoupled in acute sepsis and correlate with clinical severity

Sepsis is a critical illness characterized by dysregulated inflammatory responses lacking counter-regulation. Specialized proresolving mediators are agonists for antiinflammation and for promoting resolution, and they are protective in preclinical sepsis models. Here, in human sepsis, we mapped reso...

Full description

Bibliographic Details
Main Authors: Jundi, Bakr, Lee, Do-Hyun, Jeon, Hyungkook, Duvall, Melody G, Nijmeh, Julie, Abdulnour, Raja-Elie E, Pinilla-Vera, Mayra, Baron, Rebecca M, Han, Jongyoon, Voldman, Joel, Levy, Bruce D
Other Authors: Massachusetts Institute of Technology. Research Laboratory of Electronics
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022
Online Access:https://hdl.handle.net/1721.1/143611